Laparoscopic Antireflux Surgery vs Esomeprazole Treatment for Chronic GERD

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Laparoscopic Antireflux Surgery vs Esomeprazole Treatment for Chronic GERD

GASTROESOPHAGEAL REFLUX disease (GERD) is a highly prevalent disorder caused by the reflux of gastric contents into the esophagus. It is a chronic, relapsing disease that negatively affects patients’ health-related quality of life and reduces work productivity. Consequently, a long-term management plan is required for each individual patient. Maintenance treatment with proton pump inhibitor (PP...

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Laparoscopic antireflux surgery vs esomeprazole treatment for chronic GERD: the LOTUS randomized clinical trial.

CONTEXT Gastroesophageal reflux disease (GERD) is a chronic, relapsing disease with symptoms that have negative effects on daily life. Two treatment options are long-term medication or surgery. OBJECTIVE To evaluate optimized esomeprazole therapy vs standardized laparoscopic antireflux surgery (LARS) in patients with GERD. DESIGN, SETTING, AND PARTICIPANTS The LOTUS trial, a 5-year explorat...

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Laparoscopic antireflux surgery in the elderly

Introduction Laparoscopic antireflux surgery (LARS) has shown excellent results for treatment of gastroesophageal reflux disease (GERD). With success rates between 93% and 97% and a low incidence of complications. Life expectancy in our country is increasing and more patients over 65 years of age are admitted for surgical intervention. The aim of this retrospective study was to compare reflux a...

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Is laparoscopic reoperation for failed antireflux surgery feasible?

HYPOTHESIS Laparoscopic techniques can be used to treat patients whose antireflux surgery has failed. DESIGN Case series. SETTING Two academic medical centers. PATIENTS Forty-six consecutive patients, of whom 21 were male and 25 were female (mean age, 55.6 years; range, 15-80 years). Previous antireflux procedures were laparoscopic (21 patients), laparotomy (21 patients), thoracotomy (3 p...

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Chronic Asthma and Gastro-Esophageal Reflux Disease: The Treatment Plans

Gastro-esophageal reflux disease (GERD) regularly occurs when stomach acid moves up from the stomach into the esophagus. GERD might be associated with chronic asthma symptoms such as coughing and breathlessness. According to several studies on children and adults, GERD is proven to have a close relationship with asthma.  Medication treatment via proton-pump inhibitors (PPIs), such as Omeprazole,...

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ژورنال

عنوان ژورنال: JAMA

سال: 2011

ISSN: 0098-7484

DOI: 10.1001/jama.2011.626